P-selectin, also called GMP-140, CD62, or selectin P, is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes.

P-Selectin is a calcium-dependent receptor that funtions as a cell adhesion molecule on the surfaces of activated endothelial cells. It binds to carbohydrates on neutrophils and monocytes. It is the primary ligand for the P-Selectin glycoprotein ligand-1 and is important in the initial recruitment of leukocytes and platelets during inflammation and injury.

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P selectin

Air 医学与生命科学. Viruses 医学与生命科学. Epithelial Cells 医学与生命科学. Virology P-selectin är en adhesionsmolekyl som uttrycks på aktiverade trombocyter och befrämjar kontakt med vita blodkroppar. NO är ett kroppseget ämne som har P-Selectin. engelska. Antigen, CD62P.

P-selectin is a type-1 transmembrane protein that in humans is encoded by the SELP gene.. P-selectin functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets.

#2875 FITC-Conjugated anti-human C3 chicken antibodies. €380 · Clot P-selectin glycoprotein ligand-1 (PSGL-1) on T helper 1 but not on T helper 2 cells binds to P-selectin and supports migration into inflamed skin. München av F Mobarrez · 2020 · Citerat av 9 — Moreover, platelet derived EVs, expressing platelet activation marker P-selectin and the inflammation marker, CD40 ligand, were also Inkluderar: P-Selectin, p-selectin — Visa detaljer. Taggade verk.

The R-PLEX platform offers matched sets of antibodies and calibrators for a wide menu of biomarkers. The R-PLEX Human P-Selectin Antibody Set can be used with other MSD components (see "Recommended Components" tab below) to build assays that measure P-Selectin.

as well as inhibition of the expression of the adhesion molecule P-selectin on endothelial cells. Dessa omfattar hämning av frisättning av proinflammatoriska P-selectin on endothelial cells. EMEA0.3. Serinproteaser som sekreteras av mastceller är en viktig diagnostisk markör för typ 1 allergier (exempelvis anafylaxi; endotelväggen. Inflammatoriska cytokiner inducerar det omedelbara sättet eller sättet för expression av P-selectin på endotelcellytor och P-selectin binder svagt of tumor nuclear factor-receptor 2 (TNF-R2), e-selectin, and endostatin were significantly lower after consumption of the RP diet compared with WP (p < 0.05). S Papyri , Select , in the hieratic character from the collections of the British Museum . Regnaud , P. , De primigenia vocis Kshatriyari atque de regiis insignibus P. 1.

Framför allt har arbetet fokuserats på proteinerna ICAM-1 och P-selectin som spelar en viktig roll för rekrytering av vita blodkroppar från blodet ut i vävnaden. av M Merza · 2015 · Citerat av 139 — P-selectin mediates neutrophil rolling and recruitment in acute pancreatitis. Br J Surg. 2012; 99: 246-255.
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P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. SELP / P-Selectin / CD62P selectin P (granule membrane protein 140kDa, antigen CD62) SELP encodes a 140 kD protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Background: P-Selectin/CD62P. The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin.

P-selectin, also called GMP-140, CD62, or selectin P, is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. SELP / P-Selectin / CD62P selectin P (granule membrane protein 140kDa, antigen CD62) SELP encodes a 140 kD protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells.
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This tight link is partly attributable to P-selectin, which is functional not only when expressed on the surface of activated platelets and endothelial cells, but also when shed, generating its soluble form, termed sP-selectin.

P-selectin is a host receptor for Plasmodium MSP7 ligands P-Selectin is a calcium-dependent receptor that funtions as a cell adhesion molecule on the surfaces of activated endothelial cells. It binds to carbohydrates on neutrophils and monocytes. It is the primary ligand for the P-Selectin glycoprotein ligand-1 and is important in the initial recruitment of leukocytes and platelets during inflammation and injury. P-selectin deficiency decreases tissue stiffness in Rip1-Tag2 mouse insulinomas.